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Capsaicin demonstrates TRPV1-mediated miRNA modulation, with miR-449a significantly upregulated (34-fold) in prostate cancer cells, promoting androgen receptor degradation (4050% reduction) (102)

MG-G: Conceptualization, Formal analysis, Funding acquisition, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

However, the term Metabolic Syndrome has become commonly used since its inception by the Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) in 2001 [1]

Our study demonstrated that methylated UBE2m increases the neddylation level and protein stability of NEDD4